Research News
Video showing NK-92/5.28.z, ErbB2-CAR expressing NK-92 cells, killing Her2+ breast cancer cells (MDA-MB#453).
Shown is the polarisation of lytic granula within the NK cells towards the tumor/NK cell immunological synapse and subsequent killing of target cells (green) turning blue upon apoptosis.
NK cell granula (Lysotracker) MDA-MB#453 (Cell mask) Dead cells (Sytox blue)
Enlarged regions:
Natalie Wotschel, Jiri Eitler, Torsten Tonn (University of Technology Dresden)